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This is the battle of chins, as both men have some of the worst striking defense in the division. Nick Negumereanu checks in at 26% striking defense, absorbing nearly six strikes per minute. Ike Villanueva is a little better, checking in at a 36% striking defense. However, the veteran is absorbing nearly eight strikes per minute. Negumereanu is the more well rounded of the two, as he has shown wrestling abilities. Villunueva is purely a striker, who has won fifteen of his eighteen wins via knockout. The only issue with the veteran however, is that he has been stopped in eleven of his twelve losses.
As for a prediction, I have Negumereanu winning. Between being well rounded and having never been stopped in his career, Negumereanu is the more trustable fighter. Especially in a fight where defense is completely out the window. While this fight could end on the feet, I do believe that Negumereanu will mix in a takedown. From there, he will lock in a submission victory.